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Michigan Angel Fund Tech Company Honored for AI-Driven Innovation

Thursday, May 6th, 2021

Genomenon Earns Prestigious Luis Villalobos Award for Life Sciences at the 2021 ACA Annual Summit

The Angel Capital Association (ACA) hosted a virtual celebration at its annual summit on May 5 to recognize two innovative companies and one outstanding individual contributor to the world of angel investing. The prestigious Luis Villalobos Award recognizes companies recently financed by members of the ACA that display an inspiring level of creativity, innovativeness, and ingenuity. This year, a Michigan Angel Fund portfolio company, Genomenon, Inc., was honored as the winner for the Life Sciences category.

One in 15 people suffer from a rare disease, 80 percent of which are genetically driven. Taking an average of seven years to finally receive a diagnosis, rare disease patients endure a battery of clinical visits and invasive medical tests. Genomenon shortens this diagnostic odyssey by connecting patient DNA to scientific research and putting the findings at the fingertips of the treating clinicians — empowering them to make faster genetic diagnosis and treatment decisions.  

Leveraging AI technology, the company has built the Mastermind Genomic Search Engine®, which is used by more than 1,000 genetic testing labs and hospitals worldwide. Genomenon’s AI-driven genomic data is also used by its pharmaceutical customers to gain a profound understanding of the genetic drivers for a disease to accelerate target discovery and identify genetic biomarkers for clinical trial stratification.

Coming on the heels of a successful 2020, when the company doubled its revenue and customer base, Genomenon’s flagship product has become the world’s leading genomic search engine. With more than 12,000 users in 140 countries, Mastermind has become the de facto solution used in the rare genetic disease and cancer diagnostic space. Frost and Sullivan named Genomenon the 2020 Genomic Company of the Year based on its success in the marketplace and its impact on clinical genomics.  

The Michigan Angel Fund was an early investor in Genomenon. “We all look for companies with game-changing technology and an expert team that can execute getting the product to a global market. Genomenon is such a company,” said Skip Simms, Michigan Angel Fund managing director and Ann Arbor SPARK vice president. “We are proud of this investment and potential to serve people with a quicker, effective diagnosis for better health.”

“Michigan Angel Fund has been a key partner to Genomenon — supporting the company since our founding and through our continued growth,” said Mike Klein, CEO of Genomenon. “The nomination of this award by Michigan Angel Fund and the recognition of the Angel Capital Association for this award is a great honor.”

About the Michigan Angel Fund

The Michigan Angel Fund (MAF) focuses on providing funding to capital-efficient, early-stage companies located in Michigan. It works closely with other stakeholders in the Michigan entrepreneurial ecosystem to ensure that MAF invests in the most promising companies and to ensure the future success of these companies and its investments. For more information, visit

About Genomenon

Genomenon is an AI-driven genomics company that organizes the world’s genomic knowledge to connect patient DNA to scientific research in the diagnosis and development of treatments for patients with rare genetic diseases and cancer. Genomenon was named Global Company of the Year in Clinical Genomics Interpretation by Frost & Sullivan. For more information, visit

Startup Wellness Check: Jobs, Sales Growth

Thursday, October 8th, 2020

Skip Simms oversees all of SPARK’s entrepreneurial activities including its capital programs. He was the architect of the Michigan Pre-Seed Capital Fund co-investment program, the multiple microloan programs managed by SPARK, and is the managing partner of the Michigan Angel Fund.

This is a follow-up to a previous Startup Wellness Check. Read the results from the Q2 2020 study.

How do you think the tech-based startups and early stage companies in the area are doing in 2020? Would you guess they are really struggling? Do you think they are having trouble making sales or even getting sales meetings and opportunities? Are they able to raise more capital right now?

As an investor, I am selfishly interested in the answer to those questions. So, as the third quarter came to an end, I created a short survey and sent it to the Michigan Angel Fund portfolio of companies. Eighteen CEOs replied almost immediately. (Good practice when communicating with your investors.) If you thought the responses would be doom and gloom you would be wrong — 2020 is turning out to be a growth year.

We asked seven simple questions. Here are the results.

  • Fifty-six percent of the companies have more employees today than that had at the beginning of the year. About a third have fewer.
  • Sixty-seven percent say they are hiring and will have more employees in the next six months. Thirty percent said they would have about the same. Only one company expects to have fewer.
  • Here’s a surprise: One company has all their employees back in the office or lab. Almost 90 percent have employees working totally or mostly remotely.
  • Sales: 78 percent of companies have increased revenue vs 2019. Only 11 percent have lower sales.
  • Bonus question: What online platform are you using for your virtual calls and meetings? Eighty-two percent responded Zoom.

I’m very proud of how our company leaders have adjusted to the challenges the pandemic has wrought on all of us. It’s during challenging times like this that you can embrace opportunities to get stronger. 2021 may turn out to be an awesome year.

Michigan Angel Summit 2020 Presentations

Monday, September 28th, 2020

ACA Angel Funders Report
Keynote presentation by Rick Timmins, ACA Data Analytics Chair

Washington D.C. Insights — Issues That Impact Your Portfolio
Keynote presentation by Linda L. Smith, Chair Emeritus, Angel Capital Association and Co-Chair, Global Business Angel Network

Term Sheet Basics

Exit Events – Basics for Angel Investors

Due Diligence Fundamentals 

Michigan Entrepreneurship Score Card 

Givitas: The Social Media Platform We Need Right Now

Wednesday, July 29th, 2020

The spirit of generosity and supporting our neighbors are the heart of a community. It is also the heart of Givitas, a purpose-built platform for people to request help when they’re not sure where to turn.

Led by serial entrepreneur Larry Freed, Give and Take Inc’s core products are Givitas™, the Reciprocity Ring®, and the Virtual Reciprocity Ring™. The Reciprocity Ring was originally developed about 20 years ago by Wayne Baker, a University of Michigan professor and author of All You Have to Do Is Ask, and Cheryl Baker, a social scientist.

Adam Grant, a Wharton professor and author of Give and Take was a PhD student at University of Michigan at the time and the first facilitator of the Reciprocity Ring. The Reciprocity Ring is a dynamic group exercise that teaches the power of asking for help and the value of being a giver and helping others. It also illustrates that the activity of asking for, and giving help, is a great way to create high-quality connections.

Wayne, Adam, and Cheryl formed Give and Take in 2016 with the goal to create Givitas, the online manifestation of the Reciprocity Ring, to allow people to put the practices learned in the Reciprocity Ring to use every day, and across their organization. Givitas and the Reciprocity Ring have shown that engagement, loyalty, and profitability are all outcomes of creating a generous culture.

“The process to find someone who can help with a specific problem you’re having can be long and daunting,” Freed said. “There’s also a stigma around asking for help, it is often mistakenly seen as a sign of weakness. Driven by Adam and Wayne’s research and evidence-based practice, everything we do in Givitas is focused on making it easy and efficient to ask for and to give help, while creating a collaborative community fueled by generosity. We refer to it as creating a cycle of generosity. With Givitas, there are no anonymous asks. When you join a community, you see all requests for help and all offers of help, which encourages you to make your own requests for help and to offer help to others. For those who are still reluctant to jump in and make a request, they can learn from other’s questions and answers. It also provides equal access, for all the participants, to the communities’ knowledge and experience.” Other concepts, such as a leaderboard in each community that shows who has helped others and encouraging users to show gratitude for the help they have received, further support participation in the Givitas communities.

“Givitas makes it psychologically safe and easy to ask for help, especially when you don’t know who to ask. And it makes it efficient to be a giver, to help someone, in less than five minutes a day.”

Compared to other social media platforms, where the metric of success is spending more time on a platform, Givitas is designed to provide a return in minimal time. “It doesn’t matter why you gave — it matters you did,” he said. “And what you see is that incredible things come from paying it forward, the least of which is building social capital and growing your network.”

Not only are consumers attracted to Givitas, so are investors. When he joined the company in 2017, Freed raised its first seed round, led by RPM Ventures along with participation from Invest Michigan, Grand Ventures, and a select group of angels. Freed is also an investor in the company. In 2019, the company offered a seed extension round, and the Michigan Angel Fund, administered by Ann Arbor SPARK, participated in that funding round, along with Woodward Angels, University of Michigan’s MINTS, and the current investors.

Currently, Give and Take’s products are being used by Fortune 100 companies, associations, non-profits, governments, community groups, authors/thought leaders, and many of the leading universities in the world. At a university in Europe, it led to a lifesaving ask being answered.

“In advance of an event the university was hosting,” Freed explained. “Someone made a request about their niece in Romania having a rare brain abnormality that couldn’t be helped by locally available resources and the family did not have the resources to pursue options elsewhere. One thing led to another and someone knew someone who could help and get them to the right doctor, and get it funded. The surgery was a success and it is a great example of the incredible power in asking.”

To date, more than 100,000 people have experienced the benefits of participating in the Reciprocity Ring and Givitas. With the platform’s recently launched communities for nonprofit leaders, association leaders, and Michigan-based startups, that reach is sure to be extended.

“It’s great to believe in what you’re doing,” Freed said of the company’s success. “It’s really remarkable to be able to do good and do well in life, too.”

Describing what he calls unsolicited love letters to Givitas, Freed said, “People reach out to us and say, ‘I have always wanted to help others but didn’t know how because no one wants unsolicited help,’ or ‘I thought it would be harder to give help verses asking for help, and the opposite it proving to be true.’”

“Through Givitas, I’m reminded every day that it’s a sign of strength to ask for help, that whatever company, initiative, or objective I’m focused on advancing is more important than my ego,” he added.

As for what’s next, Freed explained the company is looking to execute another round of funding in late 2020. “I am excited about where we are and what we’re doing through Givitas,” he said. “We’re finding the right points of traction within the business and are going to hit the gas where we can, with the goal of engaging more people in our growing community rooted in generosity.” To experience Givitas, join a free community by checking the resources tab on or visiting

Startup Wellness Check: How Tech Entrepreneurs are Weathering the Pandemic

Thursday, July 2nd, 2020

Skip Simms oversees all of Ann Arbor SPARK’s entrepreneurial activities including its capital programs. He was the architect of the Michigan Pre-Seed Capital Fund co-investment program, the multiple microloan programs managed by SPARK, and is the managing partner of the Michigan Angel Fund.

While we’re closing the books on the second quarter of 2020, we really only have one quarter’s worth of COVID-19 economic data to analyze. As an angel investor, I was curious about how our Michigan-based tech entrepreneurs see things today after weathering the past three months of the pandemic.

A quick survey of company execs provided perspective. We received 41 responses from Michigan-based startups and early stage tech companies that successfully or tried to raise capital the past 12 – 18 months. Below are the survey results and some of my observations, which are mostly anecdotal based on conversations with many of these leaders.

The last question was open-ended, giving respondents the chance to share what kind of help they could use from investors. While it comes at no surprise that additional capital was at the top of their list (47%), the responses confirmed the value of introductions to potential customers (20%).

Almost everyone is saying the third quarter should be up in almost every aspect. It will be interesting to see on September 30 to what degree the growth curve moves.

The survey data is displayed in the slideshow below. You can expand the window and control the slide transition using the controls.